Ampiclox: uses, side effects, mechanism, dosage and 8 frequently asked questions – Lose 20 pounds in a month diet plan

Ampiclox is a combination of two active ingredients, Ampicillin and Cloxacillin.

Ampiclox belongs to a group of medicines known as penicillin antibiotics and is used to treat various bacterial infections.

SmithKline Beecham Pharmaceutical produces it.

Ampiclox is a combination of penicillin antibiotics, commonly prescribed to provide a broader spectrum of activity, especially against penicillin-resistant infections.

It is available as tablets and oral capsules, injections, syrup and drops for newborns.

  • Ampiclox 500 (capsules)
  • Ampiclox 500 I (injection)
  • Ampiclox S (syrup)
  • Ampiclox D (drops for newborns)
  • Ampiclox 75 I (neonatal injection)

It is used to treat a wide range of bacterial infections caused by susceptible organisms, including:

  • Upper and lower respiratory tract infections,
  • Urinary tract infections
  • Middle ear infections,
  • Gastrointestinal infections
  • Bone and joint infection
  • It can be used in infections of the skin and soft tissues, such as boils or infections caused by spider bites.
  • Endocarditis – Inflammation of the heart lining and valves.
  • Impetigo – a bacterial infection of the skin characterized by small blisters full of pus.

Ampicillin exerts its effect by inhibiting the synthesis of the bacterial cell wall.

Cloxacillin inhibits the third and final stage of bacterial cell wall synthesis. Cell lysis is then mediated by autolytic enzymes of the bacterial cell wall, such as autolysins; Cloxacillin may interfere with an autolysin inhibitor.

Common side effects include,

  • Minor stomach disorders.
  • Rash spots.
  • Nausea.
  • Inflammation of blood vessels.
  • Pink or dark urine.
  • Gastrointestinal discomfort.
  • Vomiting.
  • Diarrhea.
  • Allergic reaction.
  • Hypersensitivity reactions.
  • Anemia.
  • Thrombocytopenia
  • Gas.
  • Blood in the stool.
  • Swelling of the mouth and tongue,
  • Itching.
  • Difficulty breathing.
  • Joint pain.
  • Enlargement of the lymph nodes.
  • Hives and itching in the private parts.

  • Avoid taking this medicine if you are allergic to penicillin or any other part of this medicine.
  • Ampiclox is not suitable for infants.
  • You should not use Ampiclox for a long time.
  • Avoid taking this medicine. If you have kidney or liver problems, the dose of this medicine should be lower.
  • Contraindicated in glandular fever
  • Not suitable if you have leukemia
  • Do not take if you are on a restricted sodium diet.
  • Avoid taking this medicine in case of diabetes, arthritis, psoriasis and cancer patients.
  • Use with caution if you have gout and taking allopurinol and probenecid.

These are FDA category B drugs. No risk in other studies. Please consult your doctor for specific recommendations.


  • The usual dose for adults for susceptible infections is four times a day.
  • For severe infections, the dose may be increased to 12 capsules daily.
  • The usual childhood dose for susceptible infection is four times a day. The upper dose contains 125 mg of ampicillin and 125 mg of cloxacillin.
  • Usual dose in adults for skin and soft tissue infections Osteomyelitis and other bone infections. In acute osteomyelitis, parenteral therapy for the first three weeks for another three weeks in chronic osteomyelitis, parenteral therapy for one or two months, followed by oral therapy in the episode.


  • Usual dose for adults for sepsis, meningitis, endocarditis caused by sensitive organisms 500 mg (ampicillin 250 mg and cloxacillin 250 mg) in ten ml or 1 g (ampicillin 500 mg and 500 mg) cloxacillin in 20 ml water for injections. It is given slowly for three to four minutes, repeated every six hours.
  • Doses greater than 500 mg should be administered in two different locations of no more than 500 mg in 3 ml.
  • Your doctor may suggest a dose based on your medical history and other medical conditions, physical health, and current medications. The dose also depends on the patient’s response.

Also Read

Frequently Asked Questions (FAQs)

1. What is Ampiclox used for?

Ampiclox is a combination of two active ingredients, Ampicillin and Cloxacillin. It is used in various bacterial infections, such as upper and lower respiratory tract infections, urinary tract infections, ear infections, skin infections, soft tissue infections, and so on. Check above for more.

2. What are the side effects of Ampiclox?

Common side effects include,

  • Minor stomach disorders.
  • Nausea.
  • Vomiting.
  • Diarrhea.
  • Rash spots.
  • Inflammation of blood vessels.
  • Pink or dark urine.
  • Gastrointestinal discomfort.

This is not a complete list of side effects. Check above for more.

3. Can Ampiclox treat urinary tract infection?

One of the reported indications for this medicine is urinary tract infection. However, it is recommended that you consult your doctor before using this medicine.

4. How to take it?

Use 1 hour before meals. Oral absorption of Ampiclox may be decreased due to the presence of food in the stomach. Use Ampiclox Capsules as directed by your doctor.

5. Can Ampiclox be used during pregnancy or breast-feeding?

Ampiclox contains ampicillin and cloxacillin. Both drugs are classified as Class B drugs by the FDA. This means that there are no controlled data on human tasks. It should only be used during pregnancy, when the need has been established.

6. What happens if I overdose with Ampiclox?

If you think you have taken more than the prescribed amount of this medicine, talk to a doctor immediately. Taking more than the prescribed amount can cause serious side effects.

7. What happens if I take expired Ampiclox?

Taking a single dose of expiration is unlikely to cause any side effects. However, talk to your doctor or pharmacist if you are not feeling well or ill. An expired drug may become ineffective in treating prescribed conditions. For safety reasons, it is essential that you do not use an expired medicine. You are much safer if you always stock up on unexpired drugs.

8. How is Ampiclox stored?

Store this medicine at a temperature not exceeding 25 ° C (77 ° F). The suspension must be used within seven days of delivery. Oral drops for newborns should be stored in the refrigerator, not frozen and protected within five days of delivery and protected from moisture. Keep this medicine away from children.

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